Large Molecule

Biomarker Assays

Biomarkers are central to modern drug development. As an end to end global CRO, Cliantha provides biomarker testing solutions that help sponsors generate high quality, interpretable data from discovery through late phase trials and post marketing programs.

Comprehensive Biomarker Solutions

Cliantha supports biomarker strategies across therapeutic areas and study phases, including:

  • Exploratory biomarkers for hypothesis generation and early clinical insights
  • Pharmacodynamic (PD) biomarkers to demonstrate target engagement and biological activity
  • Predictive and prognostic biomarkers to inform patient selection and trial enrichment
  • Safety biomarkers to support risk monitoring and benefit–risk evaluations
  • Translational biomarkers bridging preclinical findings to clinical outcomes
Clinical Trial Feasibility

Platforms & Technologies

Our laboratories leverage fit for purpose platforms to match biomarker complexity, sample types, and required sensitivity:

  • Immunoassays (ELISA, MSD/ECL, CLIA/CMIA, where applicable)
  • Multiplex biomarker panels for cytokines, chemokines, and soluble markers
  • Flow cytometry / immunophenotyping for cell based biomarkers and immune monitoring
  • Chromogenic and functional assays for pathway activity and coagulation-related markers
  • Cell based assays for functional readouts when mechanism requires biological response measurement
  • Hematology parameters
  • End point and kinetic assays for Special Chemistry parameters
  • Platelet function assays
Biomarker Testing Capabilities

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